Exit drenches for long-acting injections and capsules in sheep - Elders Rural Services

Exit drenches for long-acting injections and capsules in sheep

Long-acting drenches are a popular treatment choice with many sheep farmers at lambing.

If long-acting treatments are used, it should be noted that resistance to persistent treatments is common and may select further for resistance to the active(s) used. Monitoring Worm Egg Counts (WEC) during the payout period of the long-acting treatment is routinely recommended to check for effectiveness.1

An ‘exit’ or ‘tail cutter’ drench is an anthelmintic given to sheep at the end of the protection period of long-acting injectables and capsules. The use of ‘exit’ drenches following long-acting drenches is considered sound product stewardship for the betterment of sheep and wool producers and the wider industry.

The exit drench selected should be an effective short-acting drench of a different chemical class to that of the long-acting treatment.

The purpose of the exit drench is to remove worms that survived the initial treatment or during the ‘tail’ period as drench activity declined – and stop ongoing pasture contamination with worm eggs that will give rise to an increasingly resistant population.

An early exit drench is recommended if WEC exceeds 100 epg at any time during the claimed protection period of the long-acting product. 1

Depending on when you administered the long-acting treatment, the exit drench may also coincide with weaning. Administering a highly effective exit drench to ewes at this time will be both convenient and beneficial. It will remove the parasite burden, allowing them to return to suitable condition for joining and prevent the spread of resistant worms around your farm.

The additional cost of using an exit drench in combination with a long-acting injectable or capsule is a small investment compared to what’s at stake in terms of productivity and health.

Monepantel is ideal for use as an ‘exit’ drench in combination with long-acting pre-lambing treatments. It has a unique mode of action, is short-acting and delivers >99.9 per cent efficacy against a broad spectrum of sensitive nematodes, including resistant strains.2,3,4

Zolvix contains 25 g/L of monepantel, the only member of the amino-acetonitrile derivative (AAD or ‘orange’) class of anthelmintics.2

Zolvix is registered for the treatment and control of AAD-sensitive gastro-intestinal roundworms, including those resistant to macrocyclic lactones, benzimidazoles (white drenches), levamisole and morantel (clear drenches) in sheep.2

It provides very high efficacy against a broad spectrum of sensitive roundworms, including Brown stomach worm, Black scour worm and Barber’s pole worm. 4 and has an Export Slaughter Interval of 14 days.

Zolvix Plus (25 g/L monepantel + 2 g/L abamectin) is the only combination drench that delivers the power of monepantel. Its new 21-day Export Slaughter Interval is the lowest of any combination drench containing abamectin.

You should always read and follow the label directions on every product used as good environmental practice, and for optimal worm control.

Article written by Elanco for Seasons magazine. 

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1. Wormboss 2. Refer to registered label   3. Baker, K.E. et al. (2012) Efficacy of monepantel and anthelmintic combinations against multiple-resistant Haemonchus contortus in sheep, including characterisation of the nematode isolate. Vet Para 186(3-4):513-517. 4. Hosking, B. et al. (2010) A pooled analysis of the efficacy of monepantel, an amino-acetonitrile derivative against gastrointestinal nematodes of sheep. Parasitol Res 106:529-532.

Zolvix Plus contains 25 g/L monepantel and 2 g/L abamectin. Zolvix contains 25 g/L monepantel. Zolvix™, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. ©2022 Elanco or its affiliates. PM-AU-22-0279